{"title":"Release note 04.26.21","slug":"release-note-042621","body":"## RAS-CAVATICA Integration Phase 1 Completed\n\n[The Researcher Auth Service (RAS)](https://datascience.nih.gov/researcher-auth-service-initiative), sponsored by The Office of Data Science Strategy, is a service provided by NIH’s Center for Information Technology (CIT) to facilitate access to NIH’s open and controlled data assets and repositories in a consistent and user-friendly manner. \n\nThe RAS initiative is advancing data infrastructure and ecosystem goals defined in the [NIH Strategic Plan for Data Science](https://datascience.nih.gov/strategicplan). RAS has adopted the [Global Alliance for Genomics and Health (GA4GH)](https://www.ga4gh.org/) standards for integration of researcher-focused applications and data repositories over the OIDC platform.\n\nThe goal for this effort is to coordinate all cloud stacks and use RAS identically across systems. The [NCI CRDC (Cancer Research Data Commons)](https://datacommons.cancer.gov/) stack was chosen for the pilot phase to create a phased approach that should achieve the larger goals of federated data access using GA4GH Passports, with a focus on how this fits in with NIH data in general.\n\n**Phase 1 is now completed on CAVATICA**, introducing a change to the login flow when using eRA Commons:\n* When choosing login with eRA Commons on CAVATICA, you will now be redirected to the NIH RAS login screen instead of iTrust. \n* Other than the login flow change, user experience on the platform remains the same.\n\n## Recently published apps\n\nThe following apps were published in CWL1.x:\n\n* **SRA Toolkit 2.10.8** - NCBI’s collection of tools and libraries for accessing data in Sequence Read Archives format (SRA).\n* **SRA Download and Set Metadata** - a workflow that allows for downloading full SRA datasets and populating any metadata information that goes with the dataset\n* **AnnotSV 3.0.7** - structural variant annotation and raking tool.\n* **IsoformSwitchAnalyzeR 1.12.0** - a tool for differential splicing analysis, it performs statistical identification of the isoform switching while comparing two sample groups.\n* **DRIMSeq 1.16.1** - performs differential transcript usage (DTU) analyses using Dirichlet-multinomial generalized linear models.\n* **DEXSeq 1.36.0** - toolkit for testing differential exon usage in comparative RNA-Seq experiments.\n* **Differential Exon Usage with DEXSeq 1.36.0** - a workflow constructed out of DEXSeq tools, meant for a comprehensive differential splicing analysis.","_id":"608680db6471290040da0cb5","changelog":[],"createdAt":"2021-04-26T08:59:07.483Z","user":{"name":"Marko Marinkovic","username":"","_id":"5767bc73bb15f40e00a28777"},"initVersion":{"version":"1.0","_id":"5773dcfc255e820e00e1cd50"},"project":"5773dcfc255e820e00e1cd4d","__v":0}

Release note 04.26.21


## RAS-CAVATICA Integration Phase 1 Completed [The Researcher Auth Service (RAS)](https://datascience.nih.gov/researcher-auth-service-initiative), sponsored by The Office of Data Science Strategy, is a service provided by NIH’s Center for Information Technology (CIT) to facilitate access to NIH’s open and controlled data assets and repositories in a consistent and user-friendly manner. The RAS initiative is advancing data infrastructure and ecosystem goals defined in the [NIH Strategic Plan for Data Science](https://datascience.nih.gov/strategicplan). RAS has adopted the [Global Alliance for Genomics and Health (GA4GH)](https://www.ga4gh.org/) standards for integration of researcher-focused applications and data repositories over the OIDC platform. The goal for this effort is to coordinate all cloud stacks and use RAS identically across systems. The [NCI CRDC (Cancer Research Data Commons)](https://datacommons.cancer.gov/) stack was chosen for the pilot phase to create a phased approach that should achieve the larger goals of federated data access using GA4GH Passports, with a focus on how this fits in with NIH data in general. **Phase 1 is now completed on CAVATICA**, introducing a change to the login flow when using eRA Commons: * When choosing login with eRA Commons on CAVATICA, you will now be redirected to the NIH RAS login screen instead of iTrust. * Other than the login flow change, user experience on the platform remains the same. ## Recently published apps The following apps were published in CWL1.x: * **SRA Toolkit 2.10.8** - NCBI’s collection of tools and libraries for accessing data in Sequence Read Archives format (SRA). * **SRA Download and Set Metadata** - a workflow that allows for downloading full SRA datasets and populating any metadata information that goes with the dataset * **AnnotSV 3.0.7** - structural variant annotation and raking tool. * **IsoformSwitchAnalyzeR 1.12.0** - a tool for differential splicing analysis, it performs statistical identification of the isoform switching while comparing two sample groups. * **DRIMSeq 1.16.1** - performs differential transcript usage (DTU) analyses using Dirichlet-multinomial generalized linear models. * **DEXSeq 1.36.0** - toolkit for testing differential exon usage in comparative RNA-Seq experiments. * **Differential Exon Usage with DEXSeq 1.36.0** - a workflow constructed out of DEXSeq tools, meant for a comprehensive differential splicing analysis.